Faculty and Staff

Research Interests

Proteins

• Crystallographic studies of human viruses and viral proteins; molecular design

• Structural studies of proteins by nuclear magnetic resonance techniques

• Protein-DNA interaction; protein engineering; regulation of gene expression

• Reaction mechanisms of manganese in proteins; intramolecular electron transfer

• Structural & Mechanistic Biology; Protein Dynamics & Allostery

• X-ray crystallography of surface antigens and DNA-binding proteins

• Biophysical organic and analytical chemistry; computational chemistry; mass spectrometry; study of chemical reactivity, recognition, and catalysis

• Computer studies of protein structure, function, folding and dynamics; chemical physics of liquids

• Protein folding and conformational dynamics, single molecule microscopy, time resolved fluorescence, statistical information theory, amyloid formation

• Natural product total synthesis, development of synthetic vaccines, design and synthesis of complex proteins