Mark Banaszak Holl

March 3, 2015 - 11:00am
Wright Rieman Auditorium

"Folate Conjugated Polymers: Applications for Drug Delivery and Protein Inhibition"

Spring 2015 Colloquium Series

Speaker: Mark Banaszak Holl
Department of Chemistry
University of Michigan
Abstract: Folic acid is extensively studied as a targeting agent for cancer applications. Multivalent attachment to polymers and other nanomaterials is proposed to increase binding and selectivity. The avidity mechanism of folic acid conjugates of dendritic polymers will be presented. The implications of this mechanism for cancer cell targeting in vivo and for the development of a new class of protein inhibitors with enhanced resistance characteristics will be discussed.
Poster: PDF
Host: Professor Kathryn Uhrich
~ Coffee/tea will be served prior to lecture ~