Naturally derived antioxidants and antimicrobials (eugenol, carvacrol, thymol) were chemically incorporated as pendant groups into biodegradable poly(anhydride-esters) composed of ethylenediaminetetraacetic acid as backbone, and hydrolytic degradation of these polymers yielded the free compounds which exhibited bioactivity.
Carbone-Howell, AL; Stebbins, N; Uhrich, KE “Poly(anhydride-esters) Comprised Exclusively of Naturally-occurring Antimicrobials and EDTA: Antioxidant and Antibacterial Activities”, Biomacromolecules, 15 (5) 1889–1895 (2014). 10.1021/bm500303a
More Information: http://www.medscape.com/medline/abstract/24702678
Group Members: Stephan Bien-Aime and Nicholas D. Stebbins
Year of Research Highlight: 2014