Dr. K.Y. Chen's Laboratory - Nutraceuticals

Nutraceuticals and Gene Expression Publications

Chen, Z.P., Schell, J.B., and Chen, K.Y. Green tea epigallocatechin gallate shows pronounced growth inhibitory effewct on cancerous cells but not on their normal counterparts. Cancer Letters, 129, 173-179, 1998.

Lu, J.B., Ho, C.-T., Ghai, G. and Chen, K.Y. Differential effects of theaflavin monogallates on cell growth, apoptosis and Cox-2 gene expression in cancerous versus normal cells. Cancer Research, 60, 6465-6471, 2000.

Lu, J.B., Ho, C.-T., Ghai, G. and Chen, K.Y. Resveratrol analog, 3,4,4',5-tetrahydroxystilbene, differentially induces pro-apoptotic p53/BAX gene expression and inhibits the growth of transformed cells but not their normal counterparts. Carcinogenesis,22, 321-328, 2001.

Lu, J.B., Ho, C.-T. , Ghai, G. and Chen, K.Y. Resveratrol analog, 3, 4, 4', 5-tetrahydroxystilbene, differentially induces pro-apoptotic p53/Bax gene expression and inhibits the growth of transformed cells but not their normal counterparts. Carcinogenesis, 22, 321-328, 2001.

Gosslau, A. and Chen, K.Y. Nutraceuticals, apoptosis, and disease prevention. Nutrition, 20, 95 102, 2004.

Gosslau, A., Chen, M., Ho, C.-T. and Chen, K.Y. A methoxy derivative of resveratrol analog exhibits potent and striking differential growth inhibitory effect against human cancer cells. British J. Cancer, 92, 513-521, 2005.

Fang, F., Sang, S., Chen, K.Y., Gosslau, A., Ho, C.-T., and Rosen, R.T. Isolation and identification of cytotoxic compounds from bay leaf (Laurus nobilis). Food Chem. 93,497-501, 2005.

Gosslau, Gosslau, A., Pabbaraja, S., Knapp and Chen, K.Y. Trans- and cis-stilbene polyphenols induced rapid perinuclear mitochondrial clustering and p53-independent apoptosis in cancer cells but not normal cells. European J. Pharmacology, 587, 25-34, 2008.