2017 News

Prof. Enver Cagri Izgu

New Faculty Commencing Sept 1, 2017

Enver v3Biography

Enver Cagri Izgu obtained a B.Sc. degree in chemistry from the Middle East Technical University in Ankara, Turkey, where he studied asymmetric organic catalysis with Professor Ozdemir Dogan. He then moved to the United States for graduate school and earned his Ph.D. in organic chemistry from the University of Minnesota under the tutelage of Professor Thomas R. Hoye. In the Hoye Lab, he conducted the total synthesis of structurally complex and biologically potent natural plant products, developed synthetic methodologies, and designed chemical tools for NMR spectroscopic investigations of chiral carbinols. Equipped with core synthetic chemistry skills and intrigued by the grand challenge of establishing the fundamental principles of cellular life, Enver turned his focus to chemical biology and undertook a postdoctoral position in the laboratory of Professor Jack W. Szostak at Harvard University and Massachusetts General Hospital. There, he studied primitive cells (protocells) that display evolutionarily useful functions by harnessing the systems chemistry of small molecules, nucleic acids, peptides, and lipids. These studies provided insight into the template-directed chemical and enzymatic synthesis of DNA, RNA, and RNA-like informational polymers. In addition, his work led to the discovery of chemical routes for spontaneous lipidation of amino acids and peptides in protocells, which potentially links the functionalization of primitive membranes with modern biology, where the lipidation of proteins plays a major role in membrane localization and signaling.


Education

B.Sc., Middle East Technical University, 2002-2006 (Advisor: Ozdemir Dogan)

Ph.D., University of Minnesota, 2006-2012 (Advisor: Thomas R. Hoye)

Postdoctoral Fellow, Harvard University and Massachusetts General Hospital, 2012-2017 (Advisor: Jack W. Szostak)

 

Honors and Awards

Charles and Johanna Busch Biomedical Grant Award

American Cancer Society, Institutional Research Grant Early Investigator Award

Arthur Klorfein Scholarship, Marine Biological Laboratory

NASA Travel Award, Gordon Research Conference for Origins of Life, Galveston

Young Scientists Award (National Bachelors Scholarship Program), The Scientific and Technological Research Council of Turkey

 

Research Synopsis

At Rutgers, the Izgu Lab is establishing a multidisciplinary research program to advance biotechnology and life sciences by combining synthetic organic chemistry, molecular biology, and surface chemistry. Currently, the lab is working towards finding effective technologies in the fight against diseases that affect large human populations. The lab is also studying surface chemistry to develop adaptable and reusable point-of-care technologies. Other major research interest is constructing artificial cells that can mimic cellular behavior to discover ways by which lipids can introduce new and advanced functions to cell membranes.

Members of the team have the opportunity to learn a wide variety of experimental techniques and carry out both fundamental and applied research in a collaborative environment.

 

Links

Izgu Research Group

Cancer Institute of New Jersey

Rutgers Center for Lipid Research