Nanotech 5.4.23In a recent publication, Prof. Ki-Bum Lee and his research team ( collaborated with Prof. Mi-Hyeon Jang (Rutgers University, to review upcoming nanotechnology-based approaches to target neurotoxicity, neuropathy, and cardiomyopathy, three critical side effects of chemotherapy treatment [Figure 1].
Nanomaterials can have a variety of intrinsic therapeutic properties depending on their composition, shape, and size, such as anti-oxidant properties, neuroprotective effects, and cell-specific targeting. Nanomaterials can also be utilized for the selective delivery of therapeutics for either the treatment of off-target effects induced by chemotherapeutics or to selectivity deliver chemotherapeutics and prevent off-target effects from occurring. Both strategies are imperative to provide treatments for the millions of breast and ovarian cancer survivors, and for those living with cancer, as it leads to a better quality of life and provides relief from critical chemotherapeutic side effects. Overall, this review article provides insight into the current direction of nanotechnology to treat and prevent chemotherapeutic-induced diseases, as well as highlights the significant need for further research into this field to improve the lives of many cancer survivors.

PUBLICATION:  This work was recently published in Small ( “Nanotechnology Approaches for Prevention and Treatment of Chemotherapy-Induced Neurotoxicity, Neuropathy, and Cardiomyopathy in Breast and Ovarian Cancer Survivors”, Small 2023, 2300744, DOI:10.1002/smll.202300744.

CORRESPONDENCE: Prof. Ki-Bum Lee (Rutgers University),

Ki Bum Lee Ph     


Collaborator: Dr. Mi-Hyeon Jang (Rutgers University, Robert Wood Johnson Medical School)


KBLEE Group Team: Sarah Nevins, Callan D. McLoughlin, Joshua B. Stein, Yannan Hou


Callan McLoughlin

Joshua Stein

Yannan Hou