Dual-Enhanced Raman Scattering-Based Characterization of Stem Cell Differentiation Using Graphene-Plasmonic Hybrid Nanoarray
CORRESPONDENCE: Prof. Ki-Bum Lee (Rutgers University); Prof. Jeong-Woo Choi (Sogang University)
FIRST AUTHORS: Dr. Letao Yang (Rutgers University); Dr. Jin-Ho Lee (Rutgers University)
Surface-enhanced Raman scattering (SERS) has demonstrated great potential to analyze a variety of bio/chemical molecular interactions within cells in a highly sensitive and selective manner. Despite significant advancements, it remains a critical challenge to ensure high sensitivity and selectivity, while achieving uniform signal enhancement and high reproducibility for quantitative detection of targeted biomarkers within a complex stem cell microenvironment.